Hilda Ester Shepherd was appointed to the Hupeh District, China and served there from February 1939 to July 1951. She worked as a nurse in the Hankow Union Hospital. From March 1942 to December 1945, Hilda was interned by the Japanese in Shanghai.
From December 1945 to March 1947, she spent time in Britain on an extended furlough. In September 1952 Hilda was stationed in the Eastern Nigeria District where she worked in both the Queen Elizabeth Hospital, Umuahia and the Methodist Hospital, Ama Achara.
In October 1960 Hilda was transferred to Sibu, Sarawak, where she remained until she retired in December 1967.